Synthesis, Characterisation and Biological Activity of Chiral Mixed Ligand Ni(II) Complexes

摘要

Chiral Mixed Ligand (CML) metal complexes of the type [M(PMINAP)(aa)2H_(2)O], where M is Ni(II), PMINAP is sodium salt of p-methoxyisonitrosoacetophenone and aa is a chiral amino acid have been synthesized. The present CML metal complexes could also be synthesized from racemic amino acids by in situ stereoselective complexation. The metal complexes have been characterized by elemental analysis and various physico-chemical techniques. The bonding and structure of the complexes are discussed in detail on the basis of the results of various studies. The metal complexes have been screened for their biological activity against selected microbial strains.