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A Scoring System for Identifying Severe Cases of Influenza-like Illness by Comorbidity and Age - A Nationwide Cohort Analysis

机译:通过合并症和年龄识别严重流感样疾病的评分系统-全国队列分析

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From 2008 to 2010, there were 319,775 ILI inpatient cases, of which 8.82% entered ICU and 3.83% died at hospital discharge. The significant comorbidity attributes varied in each age stratum: heart failure in any age, non-dialyzed renal insufficiency in any age, cancer in school-age children up to mid-age adults, tuberculosis in the elderly, stroke in adults, congenital anomaly in children and adolescents, transplant in school-age up to adolescents, or HIV in young adults. Comorbidity vector was (heart failure, non-dialyzed renal insufficiency, cancer, tuberculosis, stroke, congenital anomaly, transplant, HIV). Age vector was (1, 1, 6<=age<45, 75<=age, 18<=age<65, 0
机译:从2008年到2010年,共有319,775例ILI住院病例,其中8.82%进入ICU,3.83%的患者因出院死亡。合并症的显着特征因年龄而异:任何年龄段的心力衰竭,任何年龄段的非透析性肾功能不全,学龄前儿童至中年成人的癌症,老年人的结核病,成人的中风,先天性异常儿童和青少年,可在学龄前移植至青少年,或在年轻人中感染HIV。合并症的载体是(心力衰竭,非透析性肾功能不全,癌症,结核病,中风,先天性异常,移植,HIV)。年龄向量是(1,1,6 <=年龄<45,75 <=年龄,18 <=年龄<65,0 <年龄<= 18,6 <=年龄<18,18 <=年龄<45)。合并症评分是合并症向量和年龄向量的点积,与住院费用(Spearman rho = 0.1885,p <0.0001)和LOS(Spearman rho = 0.1717,p <0.0001)呈显着相关。死亡时的ROC曲线下面积(AUC)为0.7454,ICU时为0.6840。风险估计模型可以帮助我们应对即将到来的严重流感流行的人口措施,并进一步优化分配资源。

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