Acute Toxic Effects of Endosulfan 35 EC (Endocel) upon Oral Gavage and Dietary Admixture in Japanese Quails

摘要

A study was conducted to determine the acute toxic effects of Endosulfan 35 EC (Endocel) in Japanese quails by oral gavage and through dietary admixture. The acute oral LD50 value of Endosulfan 35 EC (Endocel) by gavage was determined to be 141 mg kg-1 b.wt. (equivalent to 46 mg kg-1 b.wt. of Endosulfan active ingredient) with fiducial limits of 56 and 171. The Acute Dietary LC50 value of Endosulfan 35 EC (Endocel) was 3590 mg kg-1 (which is equivalent to 1197 mg kg-1 b.wt. of Endosulfan active ingredient) with fiducial limits of 2563-6925. Endosulfan was relatively more toxic (LD50 41 mg kg-1) by the oral gavage administration when compared to the dietary route (LC50 3569 mg kg-1).