Blood biochemical changes and thyroid hormones pattern of Barki ewes as affected by biological supplementation under semi-arid conditions of Egypt

摘要

This study was carried out to investigate the effect of different levels of biological additives (ZAD? and ZADO?) on some blood biochemical parameters, as well as, thyroid hormones pattern of Barki ewes during different physiological stages. Seventy five synchronized pregnant Barki ewes were randomly allotted into five equal groups (15 each). The 1st group (G1) served as control and fed on concentrate feed mixture (CFM), the 2nd and 3rd groups (G2 and G3) were fed CFM with 6 and 10 g/h/d from ZADO?, respectively. While, the 4th and 5th groups (G4 and G5) were fed CFM with 6 and 10 ml/h/d ZAD?, respectively. All groups were offered bean (Phaseolus vulgaris) straw ad libitum. Blood biochemical parameters (total proteins, liver enzymes activities, kidney functions, glucose and cholesterol) concentrations were determined. Triiodothronine (T3), thyroxin (T4) levels were also measured during the experimental period. Results indicated that total protein, albumin, globulin and glucose concentrations were significantly higher in all treated groups compared to the control group. Albumin/globulin (A/G) ratio was significantly lower in G3 compared to the other groups. Cholesterol concentration was higher (P?0.05) in ZAD groups (G4 and G5) than other groups. Blood urea nitrogen showed slightly increase in the control group than treated groups, while creatinine concentration increased insignificantly in G4. Liver enzymes activities (AST and ALT) showed a significant increase in ZADO and ZAD groups compared to the control one, Thyroid hormones (T3 and T4) tended to increase in all treated groups compared to the control. Early lactating ewes recorded the highest concentrations (P?0.05) of TP, Glo, T3 and T4. Conversely, late pregnant ewes recorded the highest values of Alb, Cho, Cr and ALT. It could be concluded that ZAD? and ZADO? have positive effects on some blood biochemical and hormonal pattern which positively reflected on physiological responses.