Hyaluronic Acid Temporalis Fascia Graft Myringoplasty Versus Temporalis Fascia Graft Myringoplasty

摘要

The aim of the work: Improving the healing rate in tympanoplasty type 1. Objectives: To Evaluate the efficacy of Esterified Hyaluronic acid in the closure of central tympanic membrane perforation when added to a temporalis fascia and to compare its success rate in term of healing and hearing, with the of the superficial temporalis fascia grafts when used alone in the closure of central tympanic membrane perforations. Material and methods: A prospective non-randomized controlled trial at ENT department, Al-Zahraa University hospital (Tertiary care university hospital) between Oct. 2013 and Oct. 2015. Adult patients presented with small central TMP were operated under general anesthesia. The healed drum was considered when the complete closure was achieved. The patients were assessed by pure tone audiometry and tympanogram pre and postoperatively. Results: Twenty-two patients classified into group A (Hyaluronic acid temporalis fascia graft myringoplasty) and group B (temporalis fascia graft myringoplasty) (11 patients in each group) were included in the study. Healing occurred in 81.82% in group A, vs 72.73% in group B (p=0.61). Conclusion: the Esterified Hyaluronic acid that can be used to improve healing of tympanic membrane perforation. There is a statistically significant difference in the results of tympanic membrane healing and air-bone conduction gap; pre & post-operatively after using Esterified Hyaluronic acid.