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Epidemiological Profile and Treatment Outcome of Childhood Tuberculosis Patients in Pune City

机译:浦那市儿童结核病患者的流行病学概况和治疗结果

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Background: Tuberculosis (TB) is a major public health problem in India. According to the Global TB Control Report 2012, the incidence of childhood TB is estimated at 191 per 100 000 population. Childhood TB (for children aged 15 years) is generally considered to be a good marker of transmission in the community. The present study was undertaken to analyse the epidemiological and clinical characteristics of childhood TB patients and the interrelationship with the treatment outcome. Methodology: This prospective study was carried out on 198 pa-tients in the age group of 0-14 years registered in all the Tuberculosis units of Pune city. All clinical information was extracted from the treatment cards and TB registers. Results: 39.4% were males, 40% were aged 5 years, 80 (40.4%) had extra-pulmonary involvement and the remaining 118 were pulmonary TB patients of whom 42 (35.6%) were smear positive. Overall cured and treatment completion rate was 185(93.5%). Poor treatment outcome was reported in 10(5%) patients.7 (3.5%) patients defaulted. 3 (1.5%) failure to treatment were reported. Conclusion: Childhood TB in high burden countries requires far more attention from the researchers and TB control staff. The best means of preventing TB in childhood is by control of adult TB.
机译:背景:结核病(TB)是印度的主要公共卫生问题。根据2012年全球结核病控制报告,儿童结核病的发病率估计为每10万人中191例。儿童结核病(<15岁的儿童)通常被认为是社区传播的良好标志。本研究旨在分析儿童结核病患者的流行病学和临床特征以及与治疗结果的相互关系。方法:这项前瞻性研究是在浦那市所有结核病部门登记的0-14岁年龄段的198位患者中进行的。所有临床信息均从治疗卡和结核病登记簿中提取。结果:男性占39.4%,年龄小于5岁的占40%,肺外受累80例(占40.4%),其余118例是肺结核患者,其中涂片阳性42例(占35.6%)。总治愈率和治疗完成率为185(93.5%)。据报道有10(5%)名患者治疗效果差。7名(3.5%)患者违约。据报告有3例(1.5%)治疗失败。结论:高负担国家的儿童结核病需要研究人员和结核病控制人员更多的关注。预防儿童期结核病的最佳方法是控制成人结核病。

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