Neuropeptide Y: Biomarker and intervention for surgical recovery

摘要

We read with interest Enman et al.'s recent publication on Neuropeptide Y (NPY) as a therapeutic target for stress-related psychiatric diseases (Enman et al., 2015). They observe that NPY has the potential to provide novel pharmacological therapy for stress-related psychiatric diseases and may have few peripheral side-effects and drug–drug interactions. Moreover, despite its short half-life, NPY has a lasting effect. Enman et al. discuss a number of animal studies in order to lay the rationale for NPY as a pharmacological therapy for stress-related disease and cite two clinical trials that are currently underway.