Three New Indole Alkaloids from Tabernaemontana divaricata

摘要

Three new monoterpene indole alkaloids, 3 α -hydroxymethyl-ibogamine ( 1 ), 3 α -acetatemethoxyl-ibogamine ( 2 ), 16 α -hydroxyl-ibogamine ( 3 ) together with six known alkaloids were isolated from the branches and leaves of Tabernaemontana divaricata (Apocynaceae). The structures of these alkaloids were determined by spectroscopic analyses. All isolated compounds showed no significant cytotoxicity against SGC-7901 gastric cancer, HeLa, and A-549 lung cancer cell lines (IC_(50)?>?20?μM). Graphical Abstract Electronic supplementary material The online version of this article (10.1007/s13659-018-0166-x) contains supplementary material, which is available to authorized users.