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Cutaneous and systematic metastasis of testicular choriocarcinoma: Case report and literature review

机译:睾丸绒毛膜癌的皮肤和系统转移:病例报告和文献复习

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Rationale: Cutaneous metastasis of testicular choriocarcinoma is exceptionally uncommon. To our knowledge, only 14 cases have been reported in the past 10 years in the pubmed. We have an uncommon case of testicular choriocarcinoma who has metastasized to the adjacent skin and organ systems. Patient concerns: An 18-year-old male was diagnosed with initial presentation of cutaneous mass at the left back. Followly,biopsy was performed under local anesthesia.Histopathological examination was consistent with the diagnosis of metastatic choriocarcinoma. Diagnoses: The histopathological assessment of the biopsied tissue, in combination with elevated serum β-HCG levels and presentation of testicular mass, indicated primary testicular choriocarcinoma with cutaneous and systemic metastasis. Interventions: Subsequently radical orchiectomy was performed. Outcomes: Despite the case completed one cycle of cisplatin-based regimen chemotherapy, he died of multiple organ dysfunction syndrome 2 months after surgery. Lessons: In this report, cutaneous metastasis with testicular choriocarcinoma is extremely rare. It is important to recognize that this unusual variant of testicular choriocarcinoma has the potential to behave aggressively and to metastasize.
机译:理由:睾丸绒毛膜癌的皮肤转移异常罕见。据我们所知,在过去的十年中,该出版物仅报道了14例。我们有一个罕见的睾丸绒毛膜癌病例,转移到邻近的皮肤和器官系统。患者担忧:一名18岁的男性被诊断出最初出现左背皮肤肿块。随后,在局部麻醉下进行活检。组织病理学检查与转移性绒毛膜癌的诊断一致。诊断:活检组织的组织病理学评估,结合血清β-HCG水平升高和睾丸肿块的表现,提示原发性睾丸绒毛膜癌伴皮肤和全身转移。干预措施:随后进行了根治性睾丸切除术。结果:尽管该病例完成了一个周期的基于顺铂的方案化疗,但他在手术后2个月死于多器官功能障碍综合征。经验教训:在此报告中,睾丸绒毛膜癌的皮肤转移极为罕见。重要的是要认识到,这种异常的睾丸绒毛膜癌变种具有攻击性和转移性的潜力。

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