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Unobserved heterogeneity in trauma patients' desire for autonomy in medical decision making in an emergency department

机译:急诊科在医疗决策中创伤患者对自主权的渴望中观察不到的异质性

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Background To evaluate unobserved heterogeneity in trauma patients' desire for autonomy in medical decision making (DAD). Material and Method This cross-sectional study at an inner-city emergency department screened 1009 patients for DAD (using the Decision Making Preference Scale of the Autonomy Preference Index), education level, and substance use. To investigate unobserved heterogeneity, a covariate adjusted finite mixture model was established. Model fit was evaluated with the Bayesian Information Criterion. Results The median age of participants was 32 years (range, 18-84 years) and 62% were male. Unobserved heterogeneity explained more variance in DAD than did sex, age, or substance use, but less variance than level of education. The best overall model fit was found with 3 latent subpopulations: 53.3% of patients with low DAD, 35.6% of patients with medium DAD, and 11.1% of patients with high DAD. Female sex and level of education showed a positive association; higher age and substance use showed a negative association with patients' DAD. Conclusions Apart from a negative association with substance use and the known associations with sex and level of education, trauma patients' DAD showed substantial variability between individuals, and this variability could not be explained by these factors.
机译:背景技术为了评估创伤患者在医疗决策中自主权的需求中未观察到的异质性。材料和方法这项在市中心急诊室进行的横断面研究对1009例DAD患者进行了筛查(使用自主偏好指数的决策偏好量表),教育水平和药物使用情况。为了研究未观察到的异质性,建立了协变量调整的有限混合模型。使用贝叶斯信息准则对模型拟合进行评估。结果受试者的中位年龄为32岁(范围18-84岁),男性为62%。与性别,年龄或物质使用相比,未观察到的异质性解释了DAD中的差异更大,但与受教育程度相比,差异较小。最佳的总体模型拟合具有3个潜在亚群:低DAD的患者为53.3%,中DAD的患者为35.6%,高DAD的患者为11.1%。女性性别与受教育程度呈正相关。较高的年龄和药物滥用与患者的DAD呈负相关。结论除了与药物使用负相关,以及与性别和受教育程度的负相关外,创伤患者的DAD表现出个体之间的显着变异性,而这些变异性不能用这些因素来解释。

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