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Multisensory principle of heart rate regulation.

机译:心率调节的多感觉原理。

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We analyzed metabolic parameters during exercise in two groups of patientswith implanted dual sensor VVIR. The first group was comprised of 14 patients (mean age 37.7 years) withimplanted Topaz pacemakers and the second of 9 patients with a Legend Plus pacemaker (mean age 44.7 years).A control group consisted of 54 healthy individuals (mean age 40.4 years). Testing was performed on treadmill,using a stepwise staircase loading CAEP protocol. The following directly measured and mathematicallycalculated parameters we used in assessing the metabolic impact of pacemaker function: minute ventilation(MV), MV/body surface, MV/body mass unit, oxygen consumption, oxygen consumption/body surface, oxygenconsumption/heart rate (oxygen pulse), oxygen consumption/body mass unit, carbon dioxide production,respiratory index. For the majority of the observed parameters statistically significant difference wasnot found between the control group and the patients with dual sensor nor single sensor controlled rateresponse. However, oxygen pulse showed a statistically significant difference when comparing the groupwith single sensor controlled rate response with dual sensor controlled rate response as well as to thecontrol group (p < 0.05). Also, the time of reaching the anaerobic threshold, as well as the durationof the exercise test were significantly longer in dual sensor guided rate. Since these pacemakers areparticularly aimed at a population of still active patients, this finding confirms their contributionto the better quality of life and justifies their use in these patients.
机译:我们分析了两组植入双传感器VVIR的患者在运动过程中的代谢参数。第一组由14名患者(平均年龄37.7岁)植入Topaz心脏起搏器组成,第二组由9例使用Legend Plus心脏起搏器(平均年龄44.7岁)组成,对照组由54名健康个体(平均年龄40.4岁)组成。使用步进楼梯加载CAEP协议在跑步机上进行测试。我们在评估起搏器功能的代谢影响时使用了以下直接测量和数学计算的参数:分钟通气(MV),MV /体表,MV /体重单位,耗氧量,耗氧量/体表,耗氧量/心率(氧脉搏),耗氧量/体重单位,二氧化碳的产生,呼吸指数。对于大多数观察到的参数,在对照组与双传感器或单传感器控制率反应的患者之间未发现统计学上的显着差异。然而,与对照组相比,单脉冲控制率反应与双传感器控制率反应组之间的氧脉冲显示出统计学上的显着差异(p <0.05)。同样,在双传感器引导速率下,达到无氧阈值的时间以及运动测试的持续时间明显更长。由于这些起搏器特别针对仍然活跃的患者群体,因此这一发现证实了它们对改善生活质量的贡献,并证明了它们在这些患者中的使用是合理的。

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