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On reducing the need for arthroplasty: benefits for patients and budgets.

机译:在减少对关节置换术的需求上:为患者和预算带来好处。

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The need for arthroplasty, especially in the hip, arises primarily because of failure to replace damaged structural proteins as a result of improper balance in essential nutrients. The principal failure is an inadequate production of elastin resulting in cartilage consisting primarily of a collagen that may be flexible but is not elastic. In spite of the fact that an excess of protein, with adequate lysine, is commonly consumed by the affluent societies, this lysine is not utilized because of the inadequate intake of ascorbic acid necessary for virtually every step of the structural protein synthetic reactions. Experiments in animals support these conclusions. It is anticipated that dietary correction in candidates for total hip replacement will be able to restore normal hip cartilage (with corresponding improvements of other structural protein deficits throughout the body) in less than a year. Adoption of this regimen should result in: (1) a greatly decreased need for arthroplasties; and (2) better results in those that are performed, with less failures and less need for revisions. The benefits include much less suffering for patients and far lower medical costs.
机译:关节置换术的需要,尤其是在髋关节中,主要是由于必需营养素的不适当平衡导致无法替换受损的结构蛋白。主要的失败是弹性蛋白的产生不足,导致软骨主要由可能是柔性但非弹性的胶原蛋白组成。尽管富裕社会通常会消耗过量的蛋白质和足够的赖氨酸,但由于结构蛋白质合成反应的每个步骤实际上都摄入了足够的抗坏血酸,因此并未使用该赖氨酸。动物实验证明了这些结论。预计在不到一年的时间内,全髋关节置换候选者的饮食校正将能够恢复正常的髋关节软骨(并相应地改善全身其他结构性蛋白质缺陷)。采用该方案应导致:(1)对关节置换术的需求大大减少; (2)所执行的结果更好,故障更少,不需要修改。好处包括减轻患者痛苦并大大降低医疗费用。

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