首页> 外文期刊>Marine Drugs >Biosynthesis of Nutraceutical Fatty Acids by the Oleaginous Marine Microalgae Phaeodactylum tricornutum Utilizing Hydrolysates from Organosolv-Pretreated Birch and Spruce Biomass
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Biosynthesis of Nutraceutical Fatty Acids by the Oleaginous Marine Microalgae Phaeodactylum tricornutum Utilizing Hydrolysates from Organosolv-Pretreated Birch and Spruce Biomass

机译:利用有机溶剂预处理的桦木和云杉生物质水解产物,通过含油海洋微藻三角藻生物合成营养食品脂肪酸。

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Polyunsaturated fatty acids (PUFAs) are essential for human function, however they have to be provided through the diet. As their production from fish oil is environmentally unsustainable, there is demand for new sources of PUFAs. The aim of the present work was to establish the microalgal platform to produce nutraceutical-value PUFAs from forest biomass. To this end, the growth of Phaeodactylum tricornutum on birch and spruce hydrolysates was compared to autotrophic cultivation and glucose synthetic media. Total lipid generated by P. tricornutum grown mixotrophically on glucose, birch, and spruce hydrolysates was 1.21, 1.26, and 1.29 g/L, respectively. The highest eicosapentaenoic acid (EPA) production (256 mg/L) and productivity (19.69 mg/L/d) were observed on spruce hydrolysates. These values were considerably higher than those obtained from the cultivation without glucose (79.80 mg/L and 6.14 mg/L/d, respectively) and also from the photoautotrophic cultivation (26.86 mg/L and 2.44 mg/L/d, respectively). To the best of our knowledge, this is the first report describing the use of forest biomass as raw material for EPA and docosapentaenoic acid (DHA) production.
机译:多不饱和脂肪酸(PUFA)对人体功能至关重要,但是必须通过饮食来提供。由于鱼油的生产在环境上是不可持续的,因此需要新的PUFA来源。本工作的目的是建立一个微藻类平台,以从森林生物质中生产具有营养价值的PUFA。为此,将白僵菌在桦树和云杉水解产物上的生长与自养栽培和葡萄糖合成培养基进行了比较。在葡萄糖,桦树和云杉水解产物上混合营养生长的三角果假单胞菌产生的总脂质分别为1.21、1.26和1.29 g / L。云杉水解产物的二十碳五烯酸(EPA)产量最高(256 mg / L),生产率最高(19.69 mg / L / d)。这些值大大高于无葡萄糖培养时的值(分别为79.80 mg / L和6.14 mg / L / d)和光合自养培养时的值(分别为26.86 mg / L和2.44 mg / L / d)。据我们所知,这是第一份描述使用森林生物质作为EPA和二十二碳五烯酸(DHA)生产原料的报告。

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