EFFECTS OF MOBILE PHONE ELECTROMAGNETIC RADIATION ON HISTOMORPHOLOGICAL AND MORPHOMETRICAL CHANGES OF THE LYMPHOID ORGANS IN THE MICE

摘要

Background & Aims : Electromagnetic waves, such as mobile wave and microwave radiation have been used in the contemporary world for many years. Considerably, the rapidly increasing use of mobile phones has led to pay more attention to the possible effects of being exposed to mobile phone radiation on lymphatic organs . This study was conducted to investigate the mentioned effects on mice. Materials & Methods : A total of 30 healthy adult female mice were divided into one control and one exposed group. The treatment group was placed in cages with exposure to electromagnetic waves with a frequency of 915-MHz for 60 consecutive days . At the end of the experiments , total and differentiated white blood cell counts as well as the levels of IgG and IgA were determined . Lymphoid organ weights were recorded and also histological sections were prepared. Results were analyzed by independent t-test (p Results : There was no death in the groups . In the exposed animals significant reduction in the spleen cells population and also follicular size and splenic weights were seen. A decrease in the number of the thymocytes and a reduction in the diameter of lymphoid follicles were observed in the thymus structure . Lymph glands were atrophied, and empty sinuses were seen in the lymphoid follicles . In addition, the number of neutrophils and monocytes as well as the IgA levels increased in the exposed group. Conclusion : Exposure to mobile phone radiation as a stimulator factor may cause histomorphological and morphometrical alterations in the lymphoid organs of the mice .