Regional anatomical peculiarity and the evident increasing inci-dence of parapharyngeal space neoplasms, have established the necessity of an adequate diagnostic approach for their verification and competent preoperative assessment. Tu-mours of the parapharyngeal space encompass a wide variety of benign or malignant neoplasms of different origins. The clinical course of 26 patients with parapharyngeal space neoplasms was analysed. A standard diagnostic algorithm for parotid neoplasms was performed, follo-wed by adequate surgical procedure with modifications. Arteriography was used only when CT or MRI suggested a glomous tumor, or possible involvement of the carotid artery, or when those tumours put the carotid artery at risk of surgical injury. The results found from statistical evaluation revealed a higher significance of CT and MRI for tumor extension, localization and comprehension. MRI was dominant for determining tumor character and facial nerve involvement. A transparotideal appro-ach including two modifications was confirmed as being the most effective. When a parapharyngeal tumor is detected deep lobe parotid neoplasms are fre-quently to be expected. Exact preoperative planning with imaging techniques and a posterolateral parotidectomy approach with an angular mandibular osteotomy produces much better postoperative results in the surgery of deep lobe parotid tumours
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