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首页> 外文期刊>Future Science OA >Novel approaches to CMV after HCT: report from the 27th European Congress of Clinical Microbiology and Infectious Diseases, Vienna, Austria, 22–25 April 2017
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Novel approaches to CMV after HCT: report from the 27th European Congress of Clinical Microbiology and Infectious Diseases, Vienna, Austria, 22–25 April 2017

机译:HCT后CMV的新颖方法:第27届欧洲临床微生物学和传染病大会的报告,奥地利维也纳,2017年4月22日至25日

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摘要

Cytomegalovirus (CMV) infection is a potentially life-threatening complication after hematopoietic cell transplan-tation (HCT). The potential availability of novel preventive therapies was therefore an important topic duringEuropean Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 2017.A member of the β-herpesvirus family, CMV is a ubiquitous pathogen that is usually acquired in childhood orearly adult life through contact with body fluids. After primary infection, the virus becomes latent and rarely causessymptoms in healthy individuals. However, in immunocompromised hosts, CMV infection can lead to invasivedisease in almost any tissue, and represents one of the most common and significant complications after allogeneicHCT.
机译:巨细胞病毒(CMV)感染是造血细胞移植(HCT)后潜在的威胁生命的并发症。因此,新型预防疗法的潜在可用性是2017年欧洲临床微生物学和传染病大会(ECCMID)的一个重要主题.CMV是β疱疹病毒家族的成员,是一种普遍存在的病原体,通常在儿童成年后或成年后通过接触获得与体液。初次感染后,该病毒会潜伏,很少引起健康个体的症状。然而,在免疫功能低下的宿主中,CMV感染可导致几乎任何组织中的侵袭性疾病,并且是同种异体HCT之后最常见,最重要的并发症之一。

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