Advances of lncRNA in autoimmune diseases

摘要

Long non-coding RNA (lncRNA) is a newly identified non-coding RNA with various regulatory functions. Recent evidence has shown how lncRNA affect the disease development at different degrees. Studies on lncRNA have made great progress in the fields of cancer diseases and generative disorders. However, the autoimmune diseases is a relatively new research area. An increasing number of studies have stated in recent years that IncRNA plays a role in the protein transport & trafficking, gene transcription and other biological processes. This review focused on the advances of lncRNA in autoimmune diseases, such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), psoriasis, autoimmune thyroid disease (AITD), Sjogren's syndrome (SS) and Crohn's disease (CD).