Corrigendum: Bacteroides fragilis Prevents Clostridium difficile Infection in a Mouse Model by Restoring Gut Barrier and Microbiome Regulation

摘要

In the original article, there was a mistake in the Supplementary Figure 3 as published. The same Figure 3 used in the original article was also used for Supplementary Figure 3 . The corrected Supplementary Figure 3 appears below. Supplementary Figure 3 B. fragilis ZY-312 inhibits colon cell apoptosis induced by C. difficile . Representative images of PAS staining (top) for Muc-2 protein visualization in HT-29 cell monolayers are shown for all groups. Microscopic observations (middle) of Vero cell morphology and viability and PI staining (bottom) of Vero cells in all groups are shown. (A) Blank control group, 5 × 10 ~(5) HT-29 or Vero cells were cultured without treatment; (B) B. fragilis group, cells were incubated with 5 × 10 ~(8) cfu B. fragilis ; (C) C. difficile group, cells were incubated with 5 × 10 ~(7) cfu C. difficile ; (D) Exclusion group, cells were infected with 5 × 10 ~(8) cfu B. fragilis for the first hour and 5 × 10 ~(7) cfu C. difficile for the second hour; (E) Competition group, cells were co-infected with B. fragilis and C. difficile ; (F) Substitution group, cells were infected with C. difficile for the first hour and B. fragilis for the second hour. The cells were incubated at 37°C under anaerobic conditions for 2 h in total. The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original Supplementary Material has been updated.