Immune Response of Goat ( Capra hircus ) Against Fasciola hepatica

摘要

The present study was aimed to evaluate the immune response of goat against Fasciola hepatica.Total 15 goats were included for this study. The goats were immunized with different somatic antigens.The immune response was assessed on the basis of PCA and IgE response. The result showed that increasedPCA response and increased IgE response found in immunized goats on 60 day post infection in compressionto control goats. The maximum PCA reaction and IgE response were observed in goat vaccinated with larvalsomatic antigens and minimum PCA reaction and IgE response were observed in goat vaccinated with adultsomatic antigens. Larval somatic antigens were found to be more potent in providing protection as comparedto Eggs and adult somatic antigens. The increased in PCA response and IgE response in infected andimmunized goat compared to infected and non-immunized goat suggested the involvement of above studiedparameters in immune response. This study also proves that larval somatic antigen of Fasciola hepatica waseffective in imparting immunity in goat.