Prevalence and Drug Sensitivity Pattern of Campylobacter jejuni Isolated from Cattle and Poultry in and Around Gondar Town, Ethiopia

摘要

A cross sectional study was conducted from October 2013 to April 2014 to estimate the prevalenceand drug sensitivity pattern of Campylobacter jejuni from fecal sample of cattle and chickens in and aroundGondar town, Ethiopia. A total of 360 fecal samples were collected from cross and local breeds of cattle (N=270)and poultry (N=90) following random sampling method. The overall prevalence of Campylobacter jejuni incattle and poultry were 21.5% (N=58) and 28.9% (N=26) respectively. Though the difference is not statisticallysignificant, slightly higher prevalence (26.9%, N=28) was recorded in male cattle than in females (18.1%, N=30);in young (22.2%, N=8) than adults (21.4%, N=50) and in cross breeds (22.9%, N=35) than local breeds (19.7%,N=23). All isolates of Campylobacter jejuni were challenged with eight commonly used and newly introducedantimicrobials to see the resistance pattern. Isolates from cattle were resistant to Penicillin, Bacitracin,Erythromycin and Cephalothin at the rate of 96.6%, 93.1% 56.9% and 43.1% respectively but susceptible toNalidixic acid (100 %), Ampicilin (87.9%), Streptomycin (77.6%) and Tetracycline (69.0%). On the other handisolates from poultry were resistant to Penicillin (100%), to Bacitracin (80.8%), to Erythromycin (53.9%) and toTetracycline (50%) though majority were susceptible to Nalidixic acid (100%), Ampicilin (80.8%) andStreptomycin (53.9%). High percentages of resistance to most of the antimicrobials tested may indicate themisuse of these agents in food animal treatment. Therefore, it is necessary to impose strictly the rules andregulations of drug administration and delivery system in the area so as to prevent the community from hazardsof drug resistant, zoonotically important diseases.