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Effect of Gamma Ray Irradiation on Friction Property of Poly(vinyl alcohol) Cast-Drying on Freeze-Thawed Hybrid Gel

机译:γ射线辐照对聚乙烯醇在冻融混合凝胶上干燥的摩擦性能的影响

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Poly(vinyl alcohol) (PVA) is a biocompatible polymer with low toxicity. It is possible to prepare physically cross-linked PVA gels having hydrogen bonds without using a cross-linking agent. The newly reported physically cross-linked PVA cast-drying (CD) on freeze-thawed (FT) hybrid gel has an excellent friction property, which is expected to be applied as a candidate material for artificial cartilage. Gamma ray sterilization for clinical applications usually causes additional chemical cross-linking and changes physical properties of gels. In this study, CD on FT hybrid gels were irradiated using gamma rays at a different dose rate and irradiance. The results showed the optimized irradiation conditions for gamma irradiated gels to retain excellent friction characteristics.
机译:聚乙烯醇(PVA)是低毒性的生物相容性聚合物。无需使用交联剂就可以制备具有氢键的物理交联的PVA凝胶。新近报道的在冻融(FT)杂化凝胶上的物理交联PVA流延干燥(CD)具有出色的摩擦性能,有望用作人造软骨的候选材料。用于临床应用的伽马射线灭菌通常会导致其他化学交联并改变凝胶的物理性质。在这项研究中,使用不同剂量率和辐照度的伽玛射线辐照FT杂合凝胶上的CD。结果表明,γ辐照凝胶的最佳辐照条件保持了优异的摩擦特性。

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