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MicroRNAs control mRNA fate by compartmentalization based on 3′ UTR length in male germ cells

机译:MicroRNA通过基于雄性生殖细胞3'UTR长度的区室化控制mRNA的命运

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摘要

Through RNA-Seq analyses, we identified 137 genes that are missing in chicken, including the long-sought-after nephrin and tumor necrosis factor genes. These genes tended to cluster in GC-rich regions that have poor coverage in genome sequence databases. Hence, the occurrence of syntenic groups of vertebrate genes that have not been observed in Aves does not prove the evolutionary loss of such genes.
机译:通过RNA-Seq分析,我们鉴定了137种在鸡中缺失的基因,包括长期寻求的肾素和肿瘤坏死因子基因。这些基因倾向于聚集在富含GC的区域中,该区域在基因组序列数据库中的覆盖率很低。因此,没有在Aves中观察到的脊椎动物基因同系群的出现并不能证明这类基因的进化损失。

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