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Cross-border outbreak of listeriosis caused by cold-smoked salmon, revealed by integrated surveillance and whole genome sequencing (WGS), Denmark and France, 2015 to 2017

机译:2015年至2017年,丹麦和法国的综合监测和全基因组测序(WGS)揭示了由冷熏鲑鱼引起的李斯特菌病的跨界爆发

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In August 2017, an outbreak of six listeriosis cases in Denmark was traced to cold-smoked salmon, using epidemiological investigations and whole-genome sequencing (WGS) analyses. Exchange of genome sequences allowed identification in France of a food isolate from a salmon-derived product and a human isolate from 2016 within the same cgMLST cluster as the Danish isolates (L2-SL8-ST8-CT771). The salmon product came from a third European Union country. WGS can rapidly link human cases and food isolates across Europe.
机译:2017年8月,丹麦通过流行病学调查和全基因组测序(WGS)分析发现了6例李斯特菌病暴发源于冷熏鲑鱼。基因组序列的交换允许在法国鉴定与丹麦分离物(L2-SL8-ST8-CT771)在同一cgMLST集群中的鲑鱼衍生产品的食品分离物和2016年的人类分离物。三文鱼产品来自欧盟的第三个国家。 WGS可以将整个欧洲的人类病例和食物分离株快速关联起来。

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