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Cervical Carcinoma in a Renal Transplant Recipient: A Case Report

机译:肾移植受者的宫颈癌:一例报告

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A range of cancer types, at increased rates, is described in renal transplant recipients receiving immunosuppression. Aside from immunodeficiency, heightened medical surveillance for cancer, lifestyle, and other risk factors all play a role. Although the relation between cancer risk and degree of immunodeficiency might not be linear, and might be different for a wide range of cancer subtypes, human papillomavirus-related cancers in long-term transplant recipients may suggest the role of even modest immunosuppression, when present long enough. High-risk human papillomavirus types are recognized as the cause of cancer of the cervix. We report a 49-year-old female renal transplant recipient diagnosed with cervical squamous cell carcinoma, 5 years after the transplant. Based on this patient, we highlight difficulties in surgical approach and the importance of close clinical follow-up including regular gynecologic screening for cervical premalignant and malignant lesions.
机译:在接受免疫抑制的肾移植受者中,多种癌症类型以增加的比率发生了描述。除了免疫缺陷外,对癌症,生活方式和其他风险因素的医疗监视也在不断提高。尽管癌症风险与免疫缺陷程度之间的关系可能不是线性的,并且对于多种癌症亚型可能是不同的,但是长期存在于长期移植受者中的人乳头瘤病毒相关的癌症可能提示即使适度的免疫抑制也可能起一定作用足够。高危型人乳头瘤病毒被认为是子宫颈癌的病因。我们报告了一位49岁的女性肾脏移植接受者,在移植后5年被诊断患有宫颈鳞状细胞癌。根据该患者,我们强调了手术方法的困难以及密切临床随访的重要性,包括定期对妇科进行宫颈癌前病变和恶性病变筛查。

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