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Surgical techniques for sciatica due to herniated disc, a systematic review

机译:椎间盘突出引起的坐骨神经痛的手术技术,系统评价

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IntroductionDisc herniation with sciatica accounts for five percent of low-back disorders but is one of the most common reasons for spine surgery. The goal of this study was to update the Cochrane review on the effect of surgical techniques for sciatica due to disc herniation, which was last updated in 2007.Materials and methodsIn April 2011, we conducted a comprehensive search in CENTRAL, MEDLINE, EMBASE, CINAHL, PEDRO, ICL, and trial registries. We also checked the reference lists and citation tracking results of each retrieved article. Only randomized controlled trials (RCT) of the surgical management of sciatica due to disc herniation were included. Comparisons including chemonucleolysis and prevention of scar tissue or comparisons against conservative treatment were excluded. Two review authors independently selected studies, assessed risk of bias of the studies and extracted data. Quality of evidence was graded according to the GRADE approach.ResultsSeven studies from the original Cochrane review were included and nine additional studies were found. In total, 16 studies were included, of which four had a low risk of bias. Studies showed that microscopic discectomy results in a significantly, but not clinically relevant longer operation time of 12?min (95?% CI 2–22) and shorter incision of 24?mm (95?% CI 7–40) compared with open discectomy, but did not find any clinically relevant superiority of either technique on clinical results. There were conflicting results regarding the comparison of tubular discectomy versus microscopic discectomy for back pain and surgical duration.ConclusionsDue to the limited amount and quality of evidence, no firm conclusions on effectiveness of the current surgical techniques being open discectomy, microscopic discectomy, and tubular discectomy compared with each other can be drawn. Those differences in leg or back pain scores, operation time, and incision length that were found are clinically insignificant. Large, high-quality studies are needed, which examine not only effectiveness but cost-effectiveness as well...
机译:简介坐骨神经痛的椎间盘突出症占腰背疾病的5%,但这是进行脊柱手术的最常见原因之一。这项研究的目的是更新Cochrane对椎间盘突出症所致坐骨神经痛手术技术效果的评价,​​该评价于2007年进行了更新.2011年4月,我们对CENTRAL,MEDLINE,EMBASE,CINAHL进行了全面搜索,PEDRO,ICL和审判注册机构。我们还检查了每篇检索文章的参考列表和引文跟踪结果。仅包括因椎间盘突出而导致的坐骨神经痛的外科治疗的随机对照试验(RCT)。排除了包括化学核裂解和瘢痕组织预防的比较,或针对保守治疗的比较。两名评价作者独立选择研究,评估研究偏倚的风险并提取数据。结果的质量根据GRADE方法进行分级。结果包括来自原始Cochrane评价的7项研究,另外发现9项研究。总共包括16个研究,其中4个偏倚风险低。研究表明,与开放式椎间盘切除术相比,显微椎间盘切除术的手术时间明显延长,但与临床无关,更长的时间为12?min(95%CI 2-22)和24?mm较短切口(95%CI 7-40)。 ,但没有发现这两种技术对临床结果的任何临床相关优势。对于腰背痛和手术时间的比较,在管状椎间盘切除术与显微椎间盘切除术的比较上存在矛盾的结果。结论由于证据量和质量有限,目前开放式椎间盘切除术,显微椎间盘切除术和管状椎间盘切除术的有效性尚无确切的结论。可以相互比较。发现的腿部或背部疼痛评分,手术时间和切口长度的差异在临床上无意义。需要进行大规模,高质量的研究,这些研究不仅要检查有效性,还要检查成本效益。

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