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首页> 外文期刊>African Journal of Pharmacy and Pharmacology >Assessment of herbal anthelmintics used by the farmers in Kirinyaga county, Kenya, for the treatment of helminthiosis in cattle
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Assessment of herbal anthelmintics used by the farmers in Kirinyaga county, Kenya, for the treatment of helminthiosis in cattle

机译:肯尼亚基里尼亚加县农民用来治疗牛的蠕虫病的草药驱虫药评估

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摘要

The aim of this study was to assess and validate the herbal anthelmintic remedies used by farmers in Kirinyaga county, Kenya for the treatment of their cattle against gastrointestinal nematodes. The herbs used were identified via questionnaire surveys through focused group discussions. The aqueous extracts of plants used:?Aspillia pluriseta,?Vernonia lasiopus,Entada leptostachya?and?Erythrina abyssinica?were prepared and using dosage between 10 and 30%, the viability of infective strongyle larvae were assessed for a period of 48 h. The results of the?in vitro?antihelmintic study indicated a high to moderate anthelmintic activity for the tested extracts.?E. leptostachya?exhibited the highest?in vitro?anthelmintic activity, while?E. abyssinica?had the lowest activity. The anthelmintic activity may have been due to the presence of saponins in the herbal remedies. There was a positive correlation between the saponin concentration and the anthelmintic activity of the extracts. In general, the?in vitroanthelmintic activity increased with the extract concentration for the medicinal plants examined.
机译:这项研究的目的是评估和验证肯尼亚Kirinyaga县农民用来治疗牲畜抗胃肠道线虫的草药驱虫药。通过重点小组讨论,通过问卷调查确定所使用的草药。制备了所用植物的水提取物:Aspillia pluriseta,Veronia lasiopus,Entada leptostachya和Erythrina asssinica,并使用10%至30%的剂量,评估了感染性圆环虫幼虫的生存力,持续48小时。体外抗蠕虫药研究的结果表明,被测提取物具有高至中等的驱虫活性。 Leptostachya表现出最高的体外驱虫活性,而E则最高。阿比西尼卡(Abyssinica)具有最低的活性。驱虫活性可能是由于草药中存在皂苷所致。皂苷浓度与提取物的驱虫活性呈正相关。一般而言,所检查的药用植物的体外驱虫活性随提取物浓度的增加而增加。

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