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Permutation Entropy Applied to the Characterization of the Clinical Evolution of Epileptic Patients under Pharmacological Treatment

机译:置换熵用于表征药物治疗癫痫患者的临床进展

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Different techniques originated in information theory and tools from nonlinear systems theory have been applied to the analysis of electro-physiological time series. Several clinically relevant results have emerged from the use of concepts, such as entropy, chaos and complexity, in analyzing electrocardiograms and electroencephalographic (EEG) records. In this work, we develop a method based on permutation entropy (PE) to characterize EEG records from different stages in the treatment of a chronic epileptic patient. Our results show that the PE is useful for clearly quantifying the evolution of the patient along a certain lapse of time and allows visualizing in a very convenient way the effects of the pharmacotherapy.
机译:信息理论和来自非线性系统理论的工具已采用了不同的技术来分析电生理时间序列。在分析心电图和脑电图(EEG)记录时,通过使用诸如熵,混沌和复杂性之类的概念已经出现了一些与临床相关的结果。在这项工作中,我们开发了一种基于置换熵(PE)的方法来表征慢性癫痫患者治疗不同阶段的EEG记录。我们的结果表明,PE可用于明确量化患者在一定时间范围内的进展情况,并可以以非常方便的方式可视化药物治疗的效果。

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