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Associations between air temperature and cardio-respiratory mortality in the urban area of Beijing, China: a time-series analysis

机译:北京市区空气温度与心肺疾病死亡率的关联:时间序列分析

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Background Associations between air temperature and mortality have been consistently observed in Europe and the United States; however, there is a lack of studies for Asian countries. Our study investigated the association between air temperature and cardio-respiratory mortality in the urban area of Beijing, China. Methods Death counts for cardiovascular and respiratory diseases for adult residents (≥15 years), meteorological parameters and concentrations of particulate air pollution were obtained from January 2003 to August 2005. The effects of two-day and 15-day average temperatures were estimated by Poisson regression models, controlling for time trend, relative humidity and other confounders if necessary. Effects were explored for warm (April to September) and cold periods (October to March) separately. The lagged effects of daily temperature were investigated by polynomial distributed lag (PDL) models. Results We observed a J-shaped exposure-response function only for 15-day average temperature and respiratory mortality in the warm period, with 21.3°C as the threshold temperature. All other exposure-response functions could be considered as linear. In the warm period, a 5°C increase of two-day average temperature was associated with a RR of 1.098 (95% confidence interval (95%CI): 1.057-1.140) for cardiovascular and 1.134 (95%CI: 1.050-1.224) for respiratory mortality; a 5°C decrease of 15-day average temperature was associated with a RR of 1.040 (95%CI: 0.990-1.093) for cardiovascular mortality. In the cold period, a 5°C increase of two-day average temperature was associated with a RR of 1.149 (95%CI: 1.078-1.224) for respiratory mortality; a 5°C decrease of 15-day average temperature was associated with a RR of 1.057 (95%CI: 1.022-1.094) for cardiovascular mortality. The effects remained robust after considering particles as additional confounders. Conclusions Both increases and decreases in air temperature are associated with an increased risk of cardiovascular mortality. The effects of heat were immediate while the ones of cold became predominant with longer time lags. Increases in air temperature are also associated with an immediate increased risk of respiratory mortality.
机译:背景技术在欧洲和美国,一直观察到气温与死亡率之间的关联。但是,亚洲国家缺乏研究。我们的研究调查了中国北京市区气温与心肺死亡率之间的关系。方法获得2003年1月至2005年8月成年居民(≥15岁)心血管疾病和呼吸系统疾病的死亡计数,气象参数和空气中颗粒物的浓度。用泊松估计两天和十五天平均温度的影响回归模型,必要时控制时间趋势,相对湿度和其他混杂因素。分别探讨了温暖时期(4月至9月)和寒冷时期(10月至3月)的影响。通过多项式分布滞后(PDL)模型研究了日温度的滞后效应。结果我们观察到仅在15天的平均温度和温暖时期以21.3°C为阈值温度下呼吸道死亡率达到J形暴露响应功能。所有其他曝光响应函数都可以视为线性函数。在温暖期,两天平均温度升高5°C时,心血管的RR为1.098(95%置信区间(95%CI):1.057-1.140),而RR为1.134(95%CI:1.050-1.224) )用于呼吸道疾病; 15天平均温度降低5°C会导致心血管疾病的死亡率达到1.040(95%CI:0.990-1.093)。在寒冷时期,两天平均温度升高5°C,呼吸道疾病的死亡率为1.149(95%CI:1.078-1.224)。 15天平均温度降低5°C会导致心血管疾病的死亡率达到1.057(95%CI:1.022-1.094)。在考虑将粒子作为其他混杂因素后,效果仍然很强劲。结论气温升高和降低均与心血管疾病死亡风险增加有关。热的影响是立竿见影的,而冷的影响则以较长的时间滞后为主。气温升高也与呼吸道疾病的死亡风险立即增加有关。

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