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Biaxial quantification of passive porcine myocardium elastic properties by region

机译:区域性被动猪心肌弹性双轴定量

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Considering accurate constitutive models is of the utmost importance to capture mechanical response of soft tissue and biomedical materials under physiological loading conditions. This paper investigated the behaviour of porcine myocardium of passive rested hearts. This was investigated by applying biaxial loads on the myocardium. The main objective of this research was to investigate the cardiac mechanics of various regions in the healthy passive of a porcine. The biaxial mechanical properties of myocardial tissue samples were captured using a biaxial testing system. The porcine heart was divided into three regions, namely: left ventricle (LV), septum and right ventricle (RV). In these regions, 18×18 mm2 equal samples were cut from six porcine passive hearts. For the LV sample, biaxial elastic modulus in the fibre direction is 33.3% larger than in the cross fibre direction. For the mid-wall sample, biaxial elastic modulus in the fibre direction is 18.8% larger than in the cross fibre direction. For the RV sample, biaxial elastic modulus in the fibre direction is 33.3% larger than in the cross fibre direction. It was concluded that the cardiac mechanics of LV, Septum and RV exhibit different mechanical behaviour. The mechanical behaviour exhibited by various regions (LV, Septum and RV) in the healthy porcine heart differs considerably. To develop adequate computational models, these data could be utilized to estimate the material parameters of the myocardium.How to cite this paper Nemavhola, F. (2017). Biaxial quantification of passive porcine myocardium elastic properties by region.Engineering Solid Mechanics, 5(3), 155-166.
机译:考虑准确的本构模型对于在生理负荷条件下捕获软组织和生物医学材料的机械响应至关重要。本文研究了被动休息心脏的猪心肌的行为。通过在心肌上施加双轴载荷进行研究。这项研究的主要目的是研究健康的被动猪中各个区域的心脏力学。使用双轴测试系统捕获心肌组织样品的双轴机械性能。猪的心脏分为三个区域,即:左心室(LV),隔膜和右心室(RV)。在这些区域中,从六个猪被动心脏中切出了18×18 mm2的相等样本。对于LV样品,纤维方向上的双轴弹性模量比纤维交叉方向上的双轴弹性模量大33.3%。对于中壁样品,纤维方向上的双轴弹性模量比纤维交叉方向上的双轴弹性模量大18.8%。对于RV样品,纤维方向的双轴弹性模量比纤维交叉方向的双轴弹性模量大33.3%。结论是,左室,隔垫和右室的心脏力学表现出不同的机械行为。在健康的猪心脏中,各个区域(LV,隔垫和RV)表现出的机械行为差异很大。为了开发足够的计算模型,可以利用这些数据来估算心肌的物质参数。如何引用本文Nemavhola,F.(2017)。区域性被动猪心肌弹性特性的双轴定量。工程固体力学,5(3),155-166。

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