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Compact UV LED Lamp with Low Heat Emissions for Biological Research Applications

机译:用于生物研究的低热量紧凑型UV LED灯

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摘要

Much biomedical research focuses on the effects of UV light on human cells. UV light sources are a prerequisite for such research. This paper presents the design and achieved performance of a UVA (Ultraviolet A: 320–400 nm) and a UVB (Ultraviolet B: 290–320 nm) LED-based lamp suitable for use in bioassays, as well as inside an incubator. Numerical simulations were used to optimise the number, layout and output power of LEDs to achieve good irradiance homogeneity while maintaining low costs. Design was optimised for the efficient transfer of generated heat away from the irradiated samples through the heatsink at the back of the lamps. The average irradiance of the target surface by the UVA lamp was 70.1 W/m 2 with a maximum deviation of 4.9%, and the average irradiance by the UVB lamp was 3.1 W/m 2 with a maximum deviation of 4.8%. With the UVA and UVB lamps, the temperature of samples undergoing irradiation in the incubator rises from 37 to 42 °C within 40 and 67 min, respectively. This by far exceeds the required UV irradiation time in most cases. Tests on Jurkat and HEK-293 cell cultures confirmed the suitability of our lamps for biomedical research.
机译:许多生物医学研究都集中在紫外线对人体细胞的影响上。紫外线光源是进行此类研究的前提。本文介绍了适用于生物测定以及孵化器内部的基于UVA(紫外线A:320-400 nm)和UVB(紫外线B:290-320 nm)LED灯的设计和实现的性能。数值模拟用于优化LED的数量,布局和输出功率,以实现良好的辐照度均匀性,同时保持低成本。设计经过优化,可有效地将生成的热量通过灯后部的散热器从被辐射的样品中转移出去。 UVA灯的目标表面的平均辐照度为70.1 W / m 2,最大偏差为4.9%,UVB灯的平均辐照度为3.1 W / m 2,最大偏差为4.8%。使用UVA和UVB灯,在培养箱中进行辐照的样品温度分别在40分钟和67分钟内从37°C升高到42°C。在大多数情况下,这远远超过了所需的紫外线照射时间。对Jurkat和HEK-293细胞培养物的测试证实了我们的灯适用于生物医学研究。

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