...
首页> 外文期刊>EJNMMI Physics >Depth of interaction determination in monolithic scintillator with double side SiPM readout
【24h】

Depth of interaction determination in monolithic scintillator with double side SiPM readout

机译:具有双面SiPM读数的整体式闪烁体中相互作用深度的确定

获取原文

摘要

BackgroundMonolithic scintillators read out by arrays of photodetectors represent a promising solution to obtain high spatial resolution and the depth of interaction (DOI) of the annihilation photon. We have recently investigated a detector geometry composed of a monolithic scintillator readout on two sides by silicon photomultiplier (SiPM) arrays, and we have proposed two parameters for the DOI determination: the difference in the number of triggered SiPMs on the two sides of the detector and the difference in the maximum collected signal on a single SiPM on each side. This work is focused on the DOI calibration and on the determination of the capability of our detector. For the DOI calibration, we studied a method which can be implemented also in detectors mounted in a full PET scanner. We used a PET detector module composed of a monolithic 20?×?20?×?10?mm3 LYSO scintillator crystal coupled on two opposite faces to two arrays of SiPMs. On each side, the scintillator was coupled to 6?×?6 SiPMs. In this paper, the two parameters previously proposed for the DOI determination were calibrated with two different methods. The first used a lateral scan of the detector with a collimated 511?keV pencil beam at steps of 0.5?mm to study the detector DOI capability, while the second used the background radiation of the 176Lu in the scintillator. The DOI determination capability was tested on different regions of the detector using each parameter and the combination of the two. ResultsWith both parameters for the DOI determination, in the lateral scan, the bias between the mean reconstructed DOI and the real beam position was lower than 0.3?mm, and the DOI distribution had a standard deviation of about 1.5?mm. When using the calibration with the radioactivity of the LYSO, the mean bias increased of about 0.2?mm but with no degradation of the standard deviation of the DOI distribution. ConclusionsThe two parameters allow to achieve a DOI resolution comparable with the state of the art, giving a continuous information about the three-dimensional interaction position of the scintillation. These results were obtained by using simple estimators and a detector scalable to a whole PET system. The DOI calibration obtained using lutetium natural radioactivity gives results comparable to the other standard method but appears more readily applicable to detectors mounted in a full PET scanner.
机译:背景技术由光电探测器阵列读出的单晶闪烁体代表了一种获得高空间分辨率和an灭光子相互作用深度(DOI)的有前途的解决方案。我们最近研究了一种由硅光电倍增管(SiPM)阵列在两侧上由单片闪烁器读数组成的探测器几何形状,并且我们为DOI确定提出了两个参数:探测器两侧触发的SiPM数量差异以及每侧单个SiPM上最大收集信号的差异。这项工作的重点是DOI校准和检测器性能的确定。对于DOI校准,我们研究了一种方法,该方法也可以在安装在完整PET扫描仪中的检测器中实施。我们使用了一个由20?×?20?×?10?mm 3 LYSO闪烁体晶体组成的PET检测器模块,该晶体在两个相对的面上耦合到两个SiPM阵列。在每侧,闪烁体都耦合到6××6 SiPM。在本文中,先前建议用于DOI测定的两个参数用两种不同的方法进行了校准。第一种方法是使用准直的511?keV铅笔束以0.5?mm的步长对探测器进行横向扫描,以研究探测器的DOI能力,而第二种方法是使用 176 Lu的背景辐射。闪烁体。使用每个参数以及两者的组合,在检测器的不同区域上测试了DOI确定能力。结果在确定DOI的两个参数的情况下,在横向扫描中,平均重构DOI与实际光束位置之间的偏差小于0.3?mm,并且DOI分布的标准偏差约为1.5?mm。当使用具有LYSO放射性的校准物时,平均偏差增加了约0.2?mm,但没有降低DOI分布的标准偏差。结论这两个参数可以实现与现有技术相当的DOI分辨率,提供有关闪烁的三维相互作用位置的连续信息。这些结果是通过使用简单的估算器和可扩展至整个PET系统的检测器获得的。使用natural天然放射性获得的DOI校准可提供与其他标准方法相当的结果,但似乎更适用于安装在完整PET扫描仪中的检测器。

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号