Background/Aims Colorectal cancer is the third most common cancer and the fourth leading cause of cancer death in Korea. Colonoscopic screening with removal of adenomas is an effective strategy for reducing the incidence and mortality of colorectal cancer. This study was conducted to investigate predictable factors of early colorectal cancer (ECC) in patients with advanced adenoma (AA), tumor in situ (Tis), and submucosal (SM) cancer diagnosed after colonoscopic polypectomy. Methods Between August 2003 and June 2012, a total of 1,001 patients who underwent colonoscopic polypectomy in Jeju National University Hospital were enrolled in this study. Results Patients were classified into four groups; non-AA, AA, Tis, and SM cancer. Compared to the AA group, the ECC group (n=50) had large adenoma size (12.2±5.9 mm vs . 15.3±6.5 mm, P 15 mm (odds ratio [OR], 4.49; 95% confidence interval [CI] 2.40-8.38), distal location (OR, 2.59; 95% CI, 1.33-5.05), and diabetes mellitus (OR, 2.10; 95% CI, 1.07-4.43) were significantly associated with ECC. Of the 12 patients with SM cancer, 5 underwent additional operations and had no remnant carcinoma. Conclusions Predictable factors of ECC after colonoscopic polypectomy may be adenoma size >15 mm, distal location and diabetes mellitus.
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机译:背景/目的结直肠癌是韩国第三大常见癌症,也是导致癌症死亡的第四大原因。结肠镜检查并去除腺瘤是降低大肠癌发病率和死亡率的有效策略。这项研究的目的是调查在结肠镜切除术后诊断出的晚期腺瘤(AA),原位肿瘤(Tis)和粘膜下(SM)癌症患者中早期大肠癌(ECC)的可预测因素。方法2003年8月至2012年6月,在济州国立大学医院共进行了1001例行结肠镜下息肉切除术的患者。结果将患者分为四组。非AA,AA,Tis和SM癌症。与AA组相比,ECC组(n = 50)的腺瘤尺寸较大(12.2±5.9 mm vs. 15.3±6.5 mm,P 15 mm(优势比[OR],4.49; 95%置信区间[CI] 2.40) -8.38),远端位置(OR,2.59; 95%CI,1.33-5.05)和糖尿病(OR,2.10; 95%CI,1.07-4.43)与ECC显着相关。在12例SM癌患者中,结论5例患者接受了额外的手术,没有残余癌的结论结论结肠镜下息肉切除术后ECC的可预测因素可能是腺瘤大小> 15 mm,远端位置和糖尿病。
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