PREPARATION AND BIOMEDICAL CHARACTERIZATION OF JELLYFISH (CHRYSAORA QUINQUECIRRHA) COLLAGENFROMSOUTHEAST COAST OF INDIA

摘要

Jellyfishes were carefully collected from Parangipettai coastal wat ers, Southeast coast of India, during p ost monsoon season. The present res earch aimed t o isolate and characterize the collagens for the first t ime from marine wat ers. Collagens (acid-solubilized and pepsin-solubilized collagens) were pr epar ed and par tially char acter ized from jellyfish, Chrysaora quinquecirrha w hole tissue (WT ) and nematocy st suspens ion (NS. T he yield of collagen was 0.48% of GSC and 1.28% of PSC on the bas is of lyophilized dry w eight. Amino acid cont ent of WT and collagenase diges ted NS rev ealed that hydroxy proline and glycine were pres ent in the amounts of 1.8 & 9.2 % and 5.14 & 28.3 % respectiv ely, moreover it w as relatively stable at 29.0.°C for 60.min. The highest utilization of collagen is in pharmaceutical applications including production of wound dress ings, vitreous implants and as carriers for drug deliv ery. Moreover, collagen is used for the production of cosmetics as it has a good moisturizing property. Thus the jellyfis h tis sues and nematocyst suspension will have potential s ource in biomedical applications , their relev ance studies are in pr ogress