STUDY OF ANTIBACTERIAL ACTIVITY OF RESINS OF BOSWELLIA SERRATA ROXB EX COLEBR., COMMIPHORA MUKUL (HOOKS EX-STOCKS) ENGL., GARDENIA RESINIFERA ROTH. AND SHOREA ROBUSTA GAERTN

摘要

Objective: To evaluate the antibacterial activity of the resins of Boswellia serrata , Commiphora mukul , Gardenia resinifera , Shorea robusta against Gram-positive bacteria namely Bacillus cereus and Staphylococcus aureus and Gram-negative bacteria namely Proteus vulgaris and Esherichia coli . Methods: Resin samples (20%) were separately prepared in ethanol, DMSO, acetone and chloroform by overnight soaking 2 g of sample in 10 ml of solvent, filtered next day and were tested for the antibacterial activity by following standard method (well diffusion). The MIC was determined for the samples exhibiting+ve activity. Results: The study revealed that resin of Shorea did not inhibit the growth of both Gram+ve and Gram-ve bacteria. The resin of Boswellia and Commiphora showed activity against B. cereus and the MIC was found to be 20 mg/ml and 200 mg/ml respectively. Resin of Gardenia exhibited activity against B. cereus (MIC–20 mg/ml and S. aureus (MIC–100 mg/ml). Conclusion: Shorea did not have any antibacterial activity. The resins of B. serrata , C. mukul , and G. resinifera exhibited activity against Gram-positive bacteria; comparable to standard antibiotic amoxicillin, but they did not have the activity against Gram-negative bacteria. The maximum zone of inhibition (ZOI) was observed against B. cereus by Boswellia serrata resin sample prepared in ethanol. Keywords: Resins, Boswellia serrata , Commiphora mukul , Gardenia resinifera , Shorea robusta, antibacterial activity, Gram positive, Gram negative