Dietary Flavonoid Phloretin Modulates Ca2+-activated K+ Channels Resulting in an Increase of Endothelial Nitric Oxide Production

G.M. Bauer; C.A. Schaefer; A. Erdogan; H. Tillmanns; B. Waldecker; C.R.W. Kuhlmann; J. Wiecha; B.M. Munz

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Dietary Flavonoid Phloretin Modulates Ca2+-activated K+ Channels Resulting in an Increase of Endothelial Nitric Oxide Production

机译：膳食类黄酮维甲酸调节Ca 2 + 激活的K + 通道，导致内皮一氧化氮产生增加

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The aim of this study was to investigate the effects of phloretin on the Ca2+-activated K+ channel with large conductance (BK_Ca) and to assess a possible contribution of the BK_Ca to phloretin-induced changes of

机译：这项研究的目的是研究百灵通对大电导（BK _{Ca ）的Ca 2 + 激活的K + 通道的影响并评估BK _{Ca 对促性腺激素释放激素引起的变化的可能贡献}}

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《International Journal of Pharmacology》 |2005年第1期|共6页
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G.M. Bauer; C.A. Schaefer; A. Erdogan; H. Tillmanns; B. Waldecker; C.R.W. Kuhlmann; J. Wiecha; B.M. Munz;
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中图分类药学;
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1. Small- and intermediate-conductance Ca2+-activated K+ channels directly control agonist-evoked nitric oxide synthesis in human vascular endothelial cells. [J] . Sheng JZ, Braun AP American Journal of Physiology . 2007,第1期

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2. Martentoxin, a large-conductance Ca2+-activated K+ channel inhibitor, attenuated TNF-α-induced nitric oxide release by human umbilical vein endothelial cells [J] . Jun Wang, Wenyi Qian, Qing Zhu, 生物医学研究杂志（英文版） . 2013,第005期

机译：Martentoxin，一种大电导的Ca2 +激活的K +通道抑制剂，减弱了人脐静脉内皮细胞TNF-α诱导的一氧化氮释放。
3. Martentoxin, a large-conductance Ca2＋-activated K＋ channel inhibitor, attenuated TNF-α-induced nitric oxide release by human umbilical vein endothelial cells [J] . Jun Wang, Wenyi Qian, Qing Zhu, 生物医学研究杂志：英文版 . 2013,第005期

机译：Martentoxin，一种大传导性的Ca2 +激活的K +通道抑制剂，减弱了人脐静脉内皮细胞TNF-α诱导的一氧化氮释放。
4. Low-intensity Ultrasound Induces a Transient Increase in Intracellular Calcium and Enhancement of Nitric Oxide Production in Bovine Aortic Endothelial Cells [C] . S. Konno, N. Sakamoto, Y. Saijo International Conference on Biomedical Engineering . 2008

机译：低强度超声诱导细胞内钙的瞬时增加，并在牛主动脉内皮细胞中提高一氧化氮产生
5. Sex differences in aortic endothelial function of diabetic rats: Possible involvement of superoxide and nitric oxide production. [D] . Han, Xiaoyuan. 2014

机译：糖尿病大鼠主动脉内皮功能的性别差异：可能涉及超氧化物和一氧化氮的产生。
6. Martentoxin a large-conductance Ca2+-activated K+ channel inhibitor attenuated TNF-α-induced nitric oxide release by human umbilical vein endothelial cells [O] . Jun Wang, Wenyi Qian, Qing Zhu, 2013

机译：Martentoxin一种大电导的Ca2 +激活的K +通道抑制剂减弱了人脐静脉内皮细胞TNF-α诱导的一氧化氮释放。
7. Dietary Flavonoid Phloretin Modulates Ca2+-activated K+ Channels Resulting in an Increase of Endothelial Nitric Oxide Production [O] . G.M. Bauer, C.A. Schaefer ., A. Erdogan ., 2004

机译：膳食类黄酮甘油蛋白调节CA2 +活化的K +通道，导致内皮一氧化氮产生的增加

Dietary Flavonoid Phloretin Modulates Ca2+-activated K+ Channels Resulting in an Increase of Endothelial Nitric Oxide Production

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