Formulation and In-Vitro Evaluation of Propranolol Hydrochloride Loaded Polycaprolactone Microspheres

摘要

Soil is the main reservoir of the genus Bacillus. Due to their ability to form spores and withstand a range of variable environmental conditions, Bacillus sp. adapts easily to diverse habitats and cause diseases. So, it is essential to find a compound which is having antimicrobial property, there by killing Bacillus an opportunist pathogen. In the present study, isolation of bacillus from the soil sample was performed and identified by 16s rRNA sequencing and submitted in genbank under the accession number EU847311. Antibacterial potential of honey was tested by disc diffusion method and compared with standards. The results obtained with honey were found to be moderate in its antibacterial activity when compared to standards.