Determination of Essential Oil Percentage with Evaluation of Antihyperlipidemic Activity of Three Natural Gums in Rats

摘要

This study was conducted to determine the essential oil percentage of three natural gums of three medicinal plant, Commiphora molmol (myrrh), Boswellia serrata (Indian frankincense) and Aloe vera (true aloe) with evaluation of the antihyperledemic activity of the extracts of the three plants in rats. After converting all resins to powder the essential oil was extracted and percentage of essential oil of all gums was determinate and also evaluation of the antihyperlipedemic activity, the powder samples of all gums were extracted with ethanol by soxhlet apparatus. Animals were divided into six groups that where feed on an atherogenic diet (AD), (Control group, Atorvastatin group, Aloe gum extract group, Frankincense gum extract group, Myrrh gum extract group and Combination of all gum extracts group). The results were referred to percentage of essential oil of myrrh, frankincense and aloe gums were (1.2), (1.5) and (0.8) percentages respectively. Results also showed significant effect of all gums extracts in decreasing the total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL) and very-low-density lipoprotein (VLDL) with increasing the high density lipoprotein (HDL) compared with control groups. The results of this study denote that the three extracts have significant antihyperlipidemic effects. These results affirm the traditional use of myrrh, frankincense and aloe gums thereby reducing the risk of obesity and cardiovascular complication like atherosclerosis.