Anti-bacterial Potential and Qualitative Phytochemical Analysis of an Invasive Alien Plant Mikania micrantha Kunth. found in Dhenkanal District of Odisha, India

摘要

The objective of the present investigation was to evaluate the antibacterial potential of n-hexane and methanolic extracts of an invasive alien plant Mikania micrantha Kunth. The antibacterial potential of the plant was tested against 13 human pathogens such as Enterococcus faecalis (MTCC- 459), Escherichia coli (MTCC- 614), Bacillus circulans (MTCC- 490), Salmonella paratyphi (MTCC- 3220), Vibrio choleriae (MTCC- 3906), Salmonella enterica typhimurium (MTCC- 98), Pseudomonas aeruginosa (MTCC- 8076), Shigella flexneri (MTCC-9543), Salmonella enterica ser typhi (MTCC-733), Bacillus subtilis (MTCC-1305), Streptococcus mitis (MTCC- 2897), Klebsiella pneumoniae (MTCC-109) and Staphylococcus aureus (MTCC-1430) using agar well diffusion method. The results of the study revealed that n-hexane extract of sample was highly effective against Pseudomonas aeruginosa whereas Staphylococcus aureus and Klebsiella pneumoniae showed no response and other test pathogens under study responded moderately. It was observed that methanolic extract had high inhibition potential against Pseudomonas aeruginosa whereas Salmonella paratyphi and Shigella flexneri showed no response and other test pathogens under study responded moderately. Phytochemical analysis revealed presence of alkaloids, steroids, terpenoids, glycosides, tannins, proteins, carbohydrates and phenolic compounds in methanolic extract whereas n- hexane extract contains steroids, terpenoids and phenolic compounds.