METABOLITE PROFILE OF VARIOUS DEVELOPMENT BREAD FRUIT LEAVES (ARTOCARPUS ALTILIS. PARKINSON. FOSBERG) AND THE IDENTIFICATION OF THEIR MAJOR COMPONENS

摘要

Empirically dry fallen of Artocarpus altilis leaves are widely used as a traditional medicine, but the green leaves that have been widely studied. Therefore, this research was conducted to compare the metabolite profile of green leaf, attached yellow, fallen yellow, fallen dry, and fermented green leaves. Comparison of flavonoid content was conduted by HPLC. Extraction was performed using Soxhlet apparature, fractionation by VLC and setrifugal chromatography. HPLC analysis of various leaves showed that the fallen dry leaves contained the highest flavonoid compound. Three compounds were isolated, compound 1 characterized Uv-Vis, IR, 1H-NMR, 13C-NMR spectroscopies and identified as sitostenone. Compound 2 showed UV spectrum typical of flavonoid with M – 392 and tentatively identified as flavon with two prenyl substituents. Coumpound 3 was identified as b-caroten based on its UV spectrum and chromatographic data