Association Between Nutrition Status and Cognitive Impairment Among Chinese Nonagenarians and Centenarians

摘要

Summary Background The association of nutrition status with cognitive impairment has been confirmed by previous studies. However, there are no relevant data from a Chinese oldest old population. Method Five hundred eighty elderly residents aged 90 years or more were investigated. Sociodemographic characteristics and lifestyle habits were collected by using a general questionnaire. Nutritional state was assessed with the Mini Nutritional Assessment (MNA) and biochemical parameters, whereas cognitive performance was evaluated by the Mini-Mental State Examination (MMSE). Multiple Logistic regression was used to analyze the association between cognitive impairment and nutrition status. Results The total prevalence rate of cognitive impairment was 55.5%, 67 (35.1%) men and 255 (65.6%) women were classified as cognitive impairment. Compared with cognitively impaired subjects, those with normal cognition had a higher MNA score (14.28?±?1.89 vs.13.51?±?1.75, p Conclusion Among Chinese nonagenarians and centenarians, there were significant associations between nutrition status and cognitive impairment. Further studies should evaluation if maintaining a good nutritional status or nutritional intervention may be effective in the management and prevention of cognitive impairment.