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Metabolic Correction in Patients Sample with Diabetes: Clinical Outcomes and Costs Reductions

机译:糖尿病患者样本中的代谢校正:临床结果和成本降低

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Diabetes is a leading cause of mortality and morbidity worldwide. Diabetes complications produce profound impact on patient’s quality of life and represent very significant economic cost to patients, their family, the government and society as a whole. Metabolic correction has been proposed as an efficient method to improve clinical outcomes and reduce costs in diabetes. Metabolic correction is a concept that supports health maintenance and promotes the healing processes by improving the body’s biochemical-physiological mechanisms. This is done by helping activate the metabolic enzymes necessary to facilitate key physiological pathways. A group of 50 patients followed a simple metabolic correction strategy based on hydration, diet, and magnesium supplementation during a 6 months period. Outcomes measures included laboratory testing, anthropometric measures and medication use including its related costs. Patients had an average weight loss of 9.4 lbs (↓5.0%) from baseline at month 3 and 12 lbs (↓6.4%) at month 6. Waist circumference decreased on average 3.7 inches (↓9.0%) from baseline at month 3 and had further decrease to 5.5 inches (↓13.4%) from baseline at month 6. Laboratory testing of average triglycerides decreased from a baseline of 156.9 to 116.7 (↓25.6%) at month 3 and maintained a reduction of ↓24.2% by month 6. Total cholesterol concentration decreased from a baseline of 181.1 mg/dL to 173.9 (↓4.0%) in month 3 and to 171.1 (↓5.5%) at month 6. Average HgA1c decreased from baseline of 7.17 to 6.52 (↓9.1%) at month 3 and maintained 6.52 at months 6. The atherogenic index decreased from 4.18 at baseline to 3.85 at month 3 (↓7.9%) and then 3.47 (17.0%) at month 6. Medication use and cost was quantified in various ways. The average baseline monthly diabetes medication cost per patient of $124.10 was reduced to $ 78.23 (↓36.7% reduction) at month 3 and to $62.80 (↓49.4% reduction) at month 6. A simple and well structured metabolic correction program that includes a significant educational component, dietary modifications and dietary supplement intake was able to maintain or improve vital signs, anthopometric and laboratory measurements that correlate with improved clinical diabetes and cardiovascular health. This outcome was achieved while decreasing the use medications at month 3 and 6 at significant cost savings.
机译:糖尿病是世界范围内死亡率和发病率的主要原因。糖尿病并发症对患者的生活质量产生深远影响,并给患者,他们的家庭,政府和整个社会带来巨大的经济损失。已经提出了代谢校正作为改善临床结果和降低糖尿病费用的有效方法。代谢矫正是一种概念,它通过改善人体的生化生理机制来支持健康维持并促进愈合过程。这是通过帮助激活促进关键生理途径所必需的代谢酶来完成的。一组50名患者在6个月内遵循了基于水合作用,饮食和镁补充的简单代谢校正策略。结果指标包括实验室测试,人体测量指标和药物使用(包括相关费用)。患者在第3个月时平均体重减轻了9.4磅(↓5.0%),在第6个月时平均减轻了12磅(↓6.4%),而在第3个月腰围平均降低了3.7英寸(↓9.0%),并且在第6个月时,从基线进一步下降到5.5英寸(↓13.4%)。在第3个月,平均甘油三酯的实验室测试从基线的156.9降低到116.7(↓25.6%),并在第6个月保持了↓24.2%的降低。胆固醇浓度从基线的181.1 mg / dL降低到第3个月的173.9(↓4.0%)和第6个月的171.1(↓5.5%)。平均HgA1c从基线的7.17降低到第3个月的6.52(↓9.1%)。并在第6个月维持6.52。动脉粥样硬化指数从基线的4.18下降至第3个月的3.85(↓7.9%),然后在第6个月下降3.47(17.0%)。用各种方式量化药物的使用和成本。每位患者每月平均基线糖尿病药物治疗费用为124.10美元,在第3个月降低至78.23美元(降低↓36.7%),在第6个月降低至62.80美元(降低↓49.4%)。教育成分,饮食调整和饮食补充摄入量能够维持或改善生命体征,人体测量和实验室测量结果,从而改善临床糖尿病和心血管健康。在减少第3和第6个月的用药量的同时,实现了这一结果,同时节省了大量成本。

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