Synthesis and characterization of different structured ZnO nanomaterial through Polyethylene Glycol along with antibacterial activity study by direct attachment to the E.coli Dh5a and S.aureus ATCC 25923 bacterial cell membrane

摘要

The development of new resistant strains of bacteria to current antibiotics has become a serious problem in the human health; therefore, there is a strong incentive to develop new bactericides. To overcome this problem Nanotechnology is expected to open new avenues to fight and prevent disease using atomic scale tailoring of materials. Here we achieve the considerable control over ZnO nanomaterials shape comprises volume percentage control of the polymer PEG. In this article, first time we present cuboid like structure to hexagonal disc to columnar structure and finally most challenging tetrapod like structure at room temperature. The products were characterized by several sophisticated instrumental techniques. Zone of inhibition study showed the enhanced biocidal activity of ZnO nanotetrapods compared with other nanostructures in repeated experiments. It demonstrated that the bactericidal efficacy of ZnO nanostructures changes with changing nanomaterials structure. Apart from this, we also investigated cell internalization process through SAED pattern.