DOES GARLIC AFFECT SERUM ADIPONECTIN AND PRO-INFLAMMATOR ADIPOKINES LEVELS IN METABOLIC SYNDROME?

摘要

It is well known that the level of inflammation in metabolic syndrome is not high and it is often called a low grade inflammation or metaflammation, indicating the metabolic association, or para inflammation, meaning an intermediate state between basal and inflammatory states. Whatever term is used, the inflammatory process that characterizes metabolic syndrome seems to have unique features of its own. However, most adipokines with pro-inflammatory properties including interleukin-6 (IL-6) and tumor necrosis factor- a (TNF- a ) are overproduced with increasing adiposity, while some adipokines with anti-inflammatory properties such as adiponectin decrease. Some evidence suggests that monocyte-derived macrophages reside in adipose tissues and may at least in part, be the source of the pro-inflammatory adipokines generated locally and in the systemic circulation (1-3)…