Synthesis of Some Novel Heterocyclic Compounds Containing Benzofuran Moiety of Potential Antimicrobial Activity

摘要

Imidazotriazole, thiazoles, quinoxaline, benzothiazine, imidazo-thiadiazole, imidazopyridine, imidazothiazole were synthesized via reaction of 3-bromoacetyl-5-bromobenzofuran with each of thiourea, phenylthiourea, thiocetamide, thiocarbamoyl pyrazole, o-phenylenediamine, o-aminothiophenol, 2-aminothia-diazole, aminotriazole, 2-aminopyridine and 2-aminothiazole. The structure of the newly synthesized compounds was confirmed by elemental analysis, IR, 1H NMR, and mass spectral data. All compounds were evaluated for their antimicrobial activities, compound 2 gave excellent results.