Schwannoma response to interferon alpha

摘要

While cranial nerve schwannomas are typically benign, slow growing tumors, they are associated with morbidity both from the neuropathies and neuralgias they can produce, as well as from the treatments used to address these tumors, typically surgery or radiation. Here we present a case report of a patient with trigeminal neuralgia secondary to schwannoma where tumor regression is seen incidentally after patient received interferon alpha for his metastatic melanoma. Highlights ? A schwannoma resulting in trigeminal neuralgia is presented. ? Treatment with interferon alpha resulted in schwannoma regression. ? Interferon alpha should be investigated further in schwannomas.