Epidermoid cysts of the cavernous sinus are very rare, especially rare for large cysts. They are benign lesions originating from ectodermal cells misplaced during closure of the neural tube. A case is presented of a 61-year-old man with 20 years of progressive blurred vision and persistent numbness in the area of the ophthalmic and maxillary divisions of the right trigeminal nerve. MRI is the investigation of choice. Excellent recovery can be brought about through microscopic total resection without complications. So, postoperative outcome have no direct relationship with tumor size, rather with surgical strategy. Highlights ? We report the treatment of a rare large epidermoid cyst of the cavernous sinus and a review of the relevant literature. ? We think postoperative outcome have no direct ralationship with tumor size, rather with surgical strategy. ? There are many shortcomings of our page, but hope the report can serve as a guidance of the treatment of epidermoid cysts of the cavernous sinus.
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