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A giant invasive parasagittal meningioma with recurrent seizures in a young female: A case report and review of literature

机译:一名年轻女性反复发作的巨大浸润性矢状旁脑膜瘤:一例病例报告并文献复习

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IntroductionParasagittal meningiomas (PM) are very common intracranial lesion but their occurrence in young adult is very rare. Most giant PM are characterized with the invasion of the superior sagittal sinus and form very huge collaterals which makes surgical resection very difficult. The origin of meningioma is still a matter of debate which make our case much more puzzling. We therefore reviewed detailed literature on the etiologies of meningioma as well.Case presentationWe present a case of 24-years old young lady with history of seizures, blurred vision, intermittent tremors and occasional dropping of objects on the right arm. She had dizziness, headaches, tinnitus and paresthesia on the right side with loss of smell. She had a transient amaurosis fugax once before presenting to us. MRI done revealed a huge tumor compression on the left fronto-parietal gyrus and invading the superior sagittal sinus (SSS). The goal of surgery in this young lady was to preserve the SSS completely, stop frequent seizures and also preserve eloquent areas since the lesion was lying directly on the focal motor area. With a good preoperative evaluation and careful resection of the tumor, we achieved total resection without any further neurologic complications.ConclusionWe believe the etiology of meningioma in our patients started at childhood and progress to this giant status. We therefore suggest that neurosurgeon's screen children early to detect meningiomas before they advance into giant stages. Two years follow-up after surgery showed no tumor recurrence.
机译:引言旁矢状脑膜瘤(PM)是非常常见的颅内病变,但在年轻人中很少发生。大多数巨型PM的特征在于上矢状窦的侵犯并形成非常大的侧支,这使得手术切除非常困难。脑膜瘤的起源仍然是一个争论的问题,这使我们的情况更加令人困惑。因此,我们也回顾了有关脑膜瘤病因的详细文献。她右侧有头晕,头痛,耳鸣和感觉异常,并伴有异味。在向我们介绍之前,她曾经有过短暂的黑桃病。 MRI检查显示左额顶回有巨大的肿瘤压迫,并侵犯了上矢状窦(SSS)。这位年轻女士的手术目标是完全保留SSS,停止频繁的癫痫发作并保留雄辩的区域,因为病变直接位于局灶性运动区域。通过良好的术前评估和仔细的肿瘤切除,我们实现了全切除,而没有任何进一步的神经系统并发症。结论我们相信患者脑膜瘤的病因始于儿童期,并发展到这种巨大的状态。因此,我们建议神经外科医生的筛查儿童在进入巨大阶段之前尽早发现脑膜瘤。手术后两年的随访未发现肿瘤复发。

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