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Epidemiological Profile of Femoral Head Osteonecrosis in the North Indian Population

机译:北印度人口股骨头坏死的流行病学概况

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Background: There are limited studies on the epidemiology of femoral head osteonecrosis in Indian population. This study was designed to look for the risk factors of osteonecrosis hip and to assess the severity as per radiological staging (Association Research Circulation Osseous [ARCO]) and clinical score (Harris hip score [HHS]). Materials and Methods: 249 patients (382 hips) of osteonecrosis femoral head (ONFH) who were evaluated at our center between January 1, 2005, and June 30, 2013, were included in this retrospective study. The details of history, clinical examination, radiological grading, and HHS were entered into a proforma. Results: The mean age was 34.71 years (range 14-70 years) and 70.28% ( n =175) patients were between 20 and 40 years. Male to female ratio was 5:1. Bilateral ONFH was observed in 53.41% ( n =133) patients. In atraumatic conditions, bilateral involvement was seen in 61.61% (130/211) patients. Steroid administration (37.3%, 93/249) was most commonly observed in the patients followed by idiopathic in 21.3% (53/249) patients, chronic alcohol consumption in 20.1% (50/249) patients, and trauma in 15.3% (38/249) patients. There were 48% (185/382) hips in ARCO Stage 2 followed by 33% (125/382) in Stage 3 and 16% (61/382) in Stage 4. The mean HHS was 80.97 ± 14.35 in unilateral ONFH. The mean HHS was 72.79 ± 14.43 and 80.07 ± 13.52 in more involved hip and in less involved hip, respectively, in bilateral ONFH. The ARCO staging had statistically significant correlation with HHS (Pearson's correlation coefficient r = ?0.783, P < 0.01) in unilateral ONFH patients and more severely affected hip in bilateral (Pearson's correlation coefficient r = ?0.654, P < 0.01) ONFH, but it did not show any association with less involved hip in bilateral cases. Conclusion: ONFH in the North Indian patients is a disease of young individuals with male predominance. Steroid intake is most commonly observed in these patients followed by idiopathic, chronic alcohol consumption, and trauma.
机译:背景:印度人群股骨头坏死的流行病学研究有限。本研究旨在寻找骨坏死髋关节的危险因素,并根据放射分期(Association Research Circulation Osseous [ARCO])和临床评分(Harris髋关节评分[HHS])评估严重程度。资料与方法:这项回顾性研究纳入了2005年1月1日至2013年6月30日期间在我们中心接受评估的249例股骨坏死股骨头(ONFH)患者(382髋)。病史,临床检查,放射学分级和HHS的详细信息已编入形式表。结果:平均年龄为34.71岁(范围为14-70岁),而70.28%(n = 175)的患者年龄在20至40岁之间。男女比例为5:1。在53.41%(n = 133)的患者中观察到双侧ONFH。在无创伤情况下,有61.61%(130/211)的患者看到双侧受累。在患者中最常见的是类固醇给药(37.3%,93/249),其次是特发性患者,占21.3%(53/249),慢性饮酒占20.1%(50/249),外伤占15.3%(38)。 / 249)患者。在ARCO第2阶段中,髋部占48%(185/382),在第3阶段中,髋部占33%(125/382),在第4阶段中,髋部占16%(61/382)。单侧ONFH的平均HHS为80.97±14.35。双侧ONFH中,受累较多的髋关节和受累较少的髋关节的平均HHS分别为72.79±14.43和80.07±13.52。在单侧ONFH患者中,ARCO分期与HHS具有统计学显着相关性(Pearson相关系数r = 0.783,P <0.01),而在双侧ONFH患者中,髋部病变更为严重(Pearson相关系数r = 0.654,P <0.01),但是在双侧病例中未显示与髋关节受累较少相关。结论:北印度患者中的ONFH是一种以男性为主的年轻人。在这些患者中最常见的是类固醇摄入,然后是特发性,慢性饮酒和创伤。

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