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首页> 外文期刊>Indian journal of thoracic and cardiovascular surgery >Surgical management of ischemic mitral regurgitation
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Surgical management of ischemic mitral regurgitation

机译:缺血性二尖瓣关闭不全的外科治疗

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ABSTRACT Introduction Ischemic mitral regurgitation (IMR) portends a dismal survival rate for the afflicted irrespective of the type of surgical intervention. The treatment of moderate IMR has been a subject of debate with recent evidence citing similar survival statistics with revascularisation alone/revascularisation with mitral valve surgery approaches. The recognition of left ventricular (LV) reverse remodelling as the key factor determining the progression of IMR has resulted in a paradigm shift in the surgical management of IMR. Materials and methods Literature review was done in Pubmed and Scopus to identify relevant articles pertaining to the pathophysiology, diagnosis and treatment of IMR with the view of writing a narrative review on the subject. Results The similar long-term outcomes following mitral valve repair/replacement strategies for IMR has led to a resurgence of interest in primarily replacing the valve employing chordal preservation techniques especially in the setting of high probability of repair failure. Although mitral valve annuloplasty remains the most utilised surgical technique in IMR correction, several ingenious techniques tackling the various components of the valve apparatus continue to evolve. Conclusions From the current understanding, IMR is primarily a valvular manifestation of ischemic ventricular disease and hence, myocardial revascularisation forms the key element in the surgical treatment of IMR with or without adjunctive mitral valve repair/replacement.
机译:摘要简介缺血性二尖瓣关闭不全(IMR)意味着无论手术干预的类型如何,患病患者的生存率均低下。中度IMR的治疗一直是争论的话题,最近的证据援引了单独的血运重建/二尖瓣手术血运重建的相似生存统计数据。左心室(LV)逆向重构是决定IMR进程的关键因素,这一认识已导致IMR外科治疗的模式转变。材料和方法在Pubmed和Scopus进行了文献综述,以鉴定与IMR的病理生理学,诊断和治疗有关的相关文章,以撰写有关该主题的叙述性评论。结果IMR的二尖瓣修复/置换策略后的类似长期结果导致人们对重新兴起兴趣,主要是采用弦保存技术来置换瓣膜,特别是在修复失败可能性较高的情况下。尽管二尖瓣瓣环成形术仍是IMR矫正中使用最多的外科技术,但针对瓣膜装置各个组件的几种巧妙技术仍在不断发展。结论从目前的理解来看,IMR主要是缺血性心室疾病的瓣膜表现,因此,心肌血运重建是外科手术治疗伴或不伴有辅助性二尖瓣修复/置换的IMR的关键要素。

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