Background: The aim of the study was to assess the thrombolysissuccess rate beyond 90 minutes. Conventionally we assess thesuccess rate at 90 minutes after thrombolysis. In our study weassessed the success rate at 120 minutes and at 180 minutes.Methods and Results: 200 STEMI patients were enrolled. About65% are anterior wall MI, remaining are Inferior wall MI. Mediandelay was 4.5 hours on average. All are thrombolysed withstreptokinase after ruling out contraindication for thrombolysis.Success rate at 90 minutes were 42%, at 120 minutes were additional18% and at 120 minutes were additional 11%. Echo was doneto all the patients before thrombolysis, 24 hours, before dischargeand at 1 month. Ejection fraction in all the groups was comparablewith insignificant P value. But EF after 120 minutes was comparativelylow. Coronary angiogram was done to all the patientswithin 24 hours after thrombolysis. The TIMI flow also was comparablein all the three groups. In analysis we found that 90 minutesgroup were younger age group and had high percentage ofsingle vessel disease. The other two groups were little older andhad two vessel and triple vessel disease compared to 90 minutesgroup.Conclusions: Success rate of thrombolysis with streptokinase at90 minutes was 42% only but at 120 minutes there were additional18% and at 120 minutes were additional 11% patients with successfulthrombolysis.
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